Physics-based and data-driven mathematical models for the simulation of the heart function

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Location
KAUST

Masterclass in Numerical Analysis and Scientific Computing

Abstract

This seminar focuses on machine learning (the computers’ ability to learn based on training from large data sets) and computational science (the use of mathematical models originated from fundamental principles of physics) in solving mathematical problems of interest in real life. Similarities and differences, potentials and limitations are discussed, as well as the enormous possibilities offered by their synergistic use.  The driving application will be the simulation of the cardiac function, in both physiological and pathological regimes.

Brief Biography

Alfio Quarteroni is  Professor of Numerical Analysis at  Politecnico di Milano (Italy) and Emeritus Professor at EPFL, Lausanne. He is the founder (and director) of MOX at Politecnico di Milano (2002), the founder of MATHICSE at EPFL, Lausanne (2010), and the co-founder (and President) of MOXOFF, a spin-off company at Politecnico di Milano (2010). Co-founder of MATHESIA (2015) and of MATH&SPORT (2016).

He was Director of the Chair of Modelling and Scientific Computing at the EPFL, Lausanne (Switzerland), from 1 July 1998 to 1 December 2017.

He is the author of 24 books (several of them with multiple editions and translated into several languages), editor of 12 books, author of more than 400 papers published in international Scientific Journals and Conference Proceedings, and a member of the editorial board of 25 International Journals and Editor in Chief of two book series published by Springer.
In 2022 he was ranked n.48 in the Top Scientist-Mathematics from research.com, n.1 in Italy.
AD Scientific Index reports n.1 in Italy, n.5 in Europe, and n.35 worldwide.

Among his awards and honors are the NASA Group Achievement Award for the pioneering work in Computational Fluid Dynamics in 1992, the Fanfullino Della Riconoscenza 2006, Città di Lodi, the Premio Capo D’Orlando 2006, the Ghislieri prize 2013, the International Galileo Galilei prize for Sciences 2015, and the Euler Lecture 2017.

He is the Recipient of two ERC advanced grants: “MATHCARD” in 2008 and “iHEART” in 2017, and of two ERC PoC (Proof of Concept) grants: “Math2Ward” in 2012 and “Math4AAARisk” in 2015; recipient of the Galileian Chair from the Scuola Normale Superiore, Pisa, Italy, 2001; doctor Honoris Causa in Naval Engineering from University of Trieste, Italy, 2003; SIAM Fellow (first row) since 2009; IACM (International Association of Computational Mechanics) Fellow since 2004. He is a member of the Italian Academy of Science (Accademia Nazionale dei Lincei), the European Academy of Science, the Academia Europaea, the Lisbon Academy of Sciences, and the Istituto Lombardo di Scienze e Lettere, Honorary member of ECMI and EAMBES Fellow.

He has been invited to speak at ICM 2002 in Beijing and a plenary speaker at ICM 2006 in Madrid.

His research interests concern Mathematical Modelling, Numerical Analysis, Scientific Computing, and Application to fluid mechanics, structural analysis, geophysics, biomechanics, medicine, and the improvement of sports performance. His Group has carried out the mathematical optimization of the early Solar Impulse (the solar energy propelled airplane), and the simulation for the optimization of performances of the Alinghi yacht, the winner of two editions (2003 and 2007) of the America’s Cup.