Date: July 5, 2020.
Thesis brief: The central aortic blood pressure signal is an important source of information that contains cues about the cardiovascular system condition. Measuring this pulse wave clinically is burdensome as it can be only measured invasively with a catheter. As a result, many mathematical tools have been proposed in the past few decades to reconstruct the aortic pressure signal from the peripheral pressure signals that are usually easier to obtain noninvasively. At the distal level, the blood pressure signal is not directly useful since factors, such as length and stiffness of the arteries, play roles in changing the shape of the pressure signal significantly. So the main objective of the thesis is to reconstruct the central aortic blood pressure signal from the distorted peripheral pressure signals.