I am interested in the development of portable electrochemical and optical sensors for applications in the healthcare, food, industry and environmental sectors. In particular, I am focusing on the design and fabrication of microfluidics-based biosensor devices containing different types of micro or nanoelectrodes.

 

Education and Early Career

Dr. Sakandar Rauf received his Ph.D (Field of Study: Biosensors) from the University of Glasgow, U.K. in 2010. He obtained an MPhil degree in Micro- and Nanotechnology Enterprise from the University of Cambridge, U.K in 2005 and MPhil in Biotechnology from the National Institute for Biotechnology and Genetic Engineering (NIBGE), Pakistan in 2004. Dr. Rauf studied M.Sc. in Physical Chemistry from Islamia University Bahawalpur, Pakistan in 2001. He received Cambridge Commonwealth & DFID shared Scholarship from the University of Cambridge, Dorothy Hodgkin’s Postgraduate Award for his Ph.D. studies from the University of Glasgow and UQ Postdoctoral Research Fellowship from University of Queensland, Australia.

Research Interests

Dr. Rauf's research interests include ​Biosensors, Micro- and Nanoelectrodes, 3D electrodes, Electrohydrodynamics, Quantum dots, and Microfluidics. He is interested in the development of next-generation biomedical devices for point of care diagnostics.

Publications

  • Production of quantum dot barcodes using biological self-assembly.
    S. Rauf, A. Glidle and J.M. Cooper
    Advanced Materials, 21(40), 4020-4024, 2009
  • Electrohydrodynamic removal of non-specific colloidal adsorption at electrode interfaces. 
    S. Rauf, M.J.A. Shiddiky and M. Trau
    Chemical Communications, 50, 4813-4815, 2014     
  • Enhancing protein capture using a combination of nanoyeast single-chain fragment affinity reagents and alternating current. .electrohydrodynamic forces 
    R. Vaidyanathan, *S. Rauf, *Y.S. Grewal, L.J. Spadafora, M.J.A Shiddiky, G.A. Cangelosi and M. Trau
    Analytical Chemistry, 87(23), 11673-11681, 2015 *authors contributed equally
  • μeLCR: A microfabricated device for electrochemical detection of DNA base changes in breast cancer cell lines.
    E.J.H. Wee*, S. Rauf*, K.M. Koo, M.J.A. Shiddiky and M. Trau
    Lab Chip, 13, 4385-4391, 2013 *authors contributed equally
  • “Drill and fill” lithography: fabrication of platinum electrodes and their use in label-free immunosensing.
    S. Rauf, M.J.A. Shiddiky, M. Trau and K. Dimitrov
    RSC Advances, 3, 4189-4192, 2013
  • S. Rauf, M.J.A. Shiddiky and M. Trau, Electro hydrodynamic removal of non-specific colloidal absorption at electrode interfaces, Chemical Communication, 2014, 50, 4813-4815.
  • E.J.H. Wee, S. Rauf, M.J.A. Shiddiky, A. Dobrovic and M. Trau, DNA ligase-based strategy for quantifying heterogeneous DNA methylation without sequencing, Clinical Chemistry, 2014, DOI: 10.1373/clinchem.2014.227546.
  • Y. Wang, S. Rauf, Y. Grewal, S. Lauren, M.J.A. Shiddiky, G. Cangelosi, S. Schlücker and M. Trau, Duplex microfluid SERS detection of pathogen antigens with nano-yeast single-chain variable fragments. Analytical Chemistry, 2014, 86(19), 9930-9938.
  • S. Rauf, M.J.A. Shiddiky, M. Trau and K. Dimitrov, "Drill and fill" lithography: fabrication of platinum electrodes and their use in label-free immunosensing, RSC Advances, 2013, 3, 4189-4192.
  • S. Rauf, M.J.A. Shiddiky and M. Trau, "Drill and fill" lithography for controlled fabrication of 3D platinum electrode, Sensors and Actuators B: Chemical, 2013, 185, 543-547.
  • E.J.H. Wee*, S. Rauf*, K.M. Koo, M.J.A.  Shiddiky and M. Trau, μeLCR: A microfabricated device for electrochemical detection of DNA base changes in breast cancer cell lines, Lab Chip, 2013, 13, 4385-4391. *authors contributed equally.
  •  S. Rauf, M.J.A. Shiddiky, A. Asthana and K. Dimitrov, Fabrication and characterization of gold nanohole electrode arrays, Sensors and Actuators B: Chemical, 2012, 173, 491-496.
  • S. Rauf, A. Glidle and J.M. Cooper, Layer-by-layer quantum dots constructs using self-assembly methods, Langmuir, 2010, 26, 16934-16940.
  • S. Rauf, A.Glidle and J.M. Cooper, Application of quantum dot barcodes prepared using biological self-assembly to multiplexed immunoassays, Chemical Communications, 2010, 46, 2814-2816.
  • S. Rauf, A. Glidle and J.M. Cooper, Production of quantum dot barcodes using biological self-assembly, Advanced Materials, 2009, 21 (40), 4020-4024.
  • S. Rauf, H. Nawaz, K. Aktar, M.A. Ghauri and A.M. Khalid, Studies on sildenafil citrate (Viagra) interaction with DNA using electrochemical DNA biosensor, Biosensors and Bioelectronics, 2007, 22 (11), 2471-2477.
  • S. Rauf, D. Zhou, C. Abell, D. Klenerman and D.J. Kang, Building three-dimensional nanostructures with active enzymes by surface template layer-by-layer assembly, Chemical Communications, 2006, 16, 1721-1723.
  • S. Rauf, J.J. Gooding, K. Akhtar, M.A. Ghauri, M. Rahman, M.A. Anwar and A.M. Khalid, Electrochemical approach of anticancer drugs-DNA interaction, (Review article) Journal of Pharmaceutical and Biomedical Analysis, 2005, 37 (2), 205-217.

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Education Profile

  • Ph.D (Field of Study: Biosensors), University of Glasgow, U.K., 2010.
  • M.Phil., Micro- and Nanotechnology Enterprise, University of Cambridge, U.K., 2005.
  • M.Phil., Biotechnology, National Institute for Biotechnology and Genetic Engineering (NIBGE), Pakistan, 2004.
  • M.Sc., Physical Chemistry, Islamia University Bahawalpur, Pakistan, 2001.

Awards and Distinctions

  • 2010-2013 UQ Postdoctoral Research Fellowship, University of Queensland, Australia.
  • 2006-2010 Dorothy Hodgkin Postgraduate Award (DHPA), Research Councils U.K, University of Glasgow, U.K.
  • 2006 Best Research Paper Award 2006, Higher Education Commission of Pakistan (HEC).
  • 2004-2005 Cambridge Commonwealth & DFID shared Scholarship, University of Cambridge, U.K. ​ 

Professional Memberships

  • ​Member of Cambridge Commonwealth Society.