text mining

AI4GH Seminar Series - Variant Prioritization in Cancer: Understanding and Prediction of Cancer Driver Genes and Mutations

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B2 R5220

Sequencing has identified millions of somatic mutations in human cancers. Identifying and distinguishing cancer driver genes amongst the millions of candidate mutations remains a major challenge.

Variant Prioritization in Cancer: Understanding and Prediction of Cancer Driver Genes and Mutations

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B3 R5209

Abstract Sequencing has identified millions of somatic mutations in human cancers. Identifying and distinguishing cancer driver genes amongst the millions of candidate mutations remains a major challenge. Accurate identification of driver genes and driver mutations is critical for advancing cancer research and personalizing treatment based on accurate stratification of patients. Due to inter-tumor genetic heterogeneity, many driver mutations within a gene occur at low frequencies, which make it challenging to distinguish them from other non-driver mutations. Motivated by these challenges, we

Large-scale Text and Data Integration for Cancer Genomics Research

Prof. D, Rebholz-Schuhmann (University Cologne, Germany​)​

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B19 L3 H2

Abstract This talk will give an overview of data and text mining in the life science domain, but will also point out the use of semantic technologies for other domains. Such solutions cover the integration of heterogeneous data sources based on Semantic Web standards (e.g., TCGA, Cosmic, others), the development of smart technologies (e.g., stream processing), graph and literature analytics, and open data initiatives. Application domains are biomedical solutions in cancer genomics and targeted projects together with industrial partners exploiting Semantic Web technologies in general. The

Arwa Bin Raies defends her thesis proposal

1 min read ·
Arwa Bin Raies, a Ph.D. candidate under the supervision of Professor Vladimir Bajic, defended her thesis proposal on May 14, 2018.

Sara Althubaiti defends her Master's thesis

1 min read ·
Sara Althubaiti, a student under the supervision of Assistant Professor Robert Hoehndorf, defended her Master's thesis on November 5, 2018.

Sara Althubaiti

Ph.D. Student, Computer Science
Sara Althubaiti is currently a Ph.D. candidate in the Bio-Ontology Research Group (BORG) at King Abdullah University of Science and Technology (KAUST) under the supervision of Professor Robert Hoehndorf. Prior to this, Sara received her master's degree in computer science with a focus on bioinformatics from KAUST in December 2018. Research Interests Sara's research interests include bioinformatics, text mining, ontologies, and cancer. Her research focuses on applying machine learning methods in cancer biology and development specifically in the field of finding driver genes and mutations in

Robert Werfelmann

Robert Werfelmann obtained a Master's Degree in Computer Science program at Machine Intelligence and kNowledge Engineering (MINE) Laboratory under the supervision of Professor Xiangliang Zhang at King Abdullah University of Science and Technology (KAUST). He did his thesis in a task of Natural Language Processing where the goal is to predict the native language of the author of a non-native text. During his studies, he has built and improved skills in several topics including algorithm design and analysis, concurrent computing, computer networking, and artificial intelligence fields such as

Christophe Van Neste

Postdoctoral Research Fellow, Structural and Functional Bioinformatics
Christophe Van Neste is a Postdoctoral Fellow under the supervision of Professor Xin Gao at the Structural and Functional Bioinformatics Group (SFB) at King Abdullah University of Science and Technology (KAUST). Research Interests ​My topic interests are centered around cancer and development, specifically related to the embryonal cancer neuroblastoma and how it links to the normal development of the sympathetic neuronal system. My focus there lies on replicative stress and secondary DNA structures such as G-quadruplexes and how that impacts development or cancer stem cell maintenance. My

Arwa Bin Raies

Research Interests I am a computer scientist whose primary focus is on developing novel machine learning methods to extract useful information from complex datasets. My experience, however, has covered intellectually wide-ranging areas spanning several disciplines in computer science, biology, and chemistry. At the undergraduate level, I focused on computer networks, and I did an internship for six months at Cisco Systems Inc., and I achieved CCNA and CCNP certification. At the Master's level, however, I joined the Computational Bioscience Research Center. I was in charge of a text-mining

Adil Salhi

Adil Salhi is a Research Engineer at Prof. Xin Gao's Structural and Functional Bioinformatics Group (SFB) at King Abdullah University of Science and Technology (KAUST). Adil obtained his Ph.D. degree in Computer Science from the University of Manchester, UK. Research Interests Adil's research interests lie in the area of data and text mining of biomedical literature. The extraction of new information from disparate structured data sources, or available information buried in free-form text, requires the deployment of a wide array of tools to overcome the challenges posed by the nature and size