Research Interests

Working on projects with the Computational Bioscience Research Center (CBRC) and KAUST Smart Health Initiative (KSHI).

My research includes the prediction of protein 3D structure and function, evolution, and phylogenetic studies through various algorithms; elucidate the molecular function, framework, and dynamics of the protein by MD simulations using supercomputers. Relating the computational data to experimental data by performing biophysical assays, molecular biology, structural biology, and biochemistry experiments.

Education Profile

  • Doctor of Philosophy Ph.D. (Bioscience), KAUST, Thuwal, Saudi Arabia, 2014 – 2019
  • Master of Science (Bioinformatics), University of Mumbai, Mumbai, India, 2011-2013
  • Bachelor of Science (Biotechnology), University of Mumbai, Mumbai, India, 2008-2011

Professional Memberships

  • 2023 - present - Research Scientist, KAUST, Thuwal, Saudi Arabia
  • 2020 - 2022 - Post-doctoral fellow, KAUST, Thuwal, Saudi Arabia
  • 2013 - 2014 - Lecturer in Biotechnology and Bioinformatics - CKT College, New Mumbai, INDIA

Selected Publications

Alam, T., Alazmi, M., Naser, R., Huser, F., Momin, A. A., Walkiewicz, K. W., … Arold, S. T. (2018). Proteome-level assessment of origin, prevalence and function of Leucine-Aspartic Acid (LD) motifs. doi:10.1101/278903
Hungler, A., Momin, A., Diederichs, K., & Arold, S., T. (2016). ContaMinerand ContaBase: a webserver and database for early identification of unwantedly crystallized protein contaminants. Journal of Applied Crystallography, 49(6), 2252–2258.
Momin, A.A., Mendes, T., Barthe, P. et al. PYK2 senses calcium through a disordered dimerization and calmodulin-binding element. Commun Biol 5, 800 (2022).
Rehman, Z. U., Momin, A. A., Aldehaiman, A., Irum, T., Grünberg, R., & Arold, S. T. (2022). The exceptionally efficient quorum quenching enzyme LrsL suppresses Pseudomonas aeruginosa biofilm production. Frontiers in Microbiology, 13.
Aldehaiman, A., Momin, A. A., Restouin, A., Wang, L., Shi, X., Aljedani, S., … Arold, S. T. (2021). Synergy and allostery in ligand binding by HIV-1 Nef. Biochemical Journal, 478(8), 1525–1545.
Momin, A. A., Hameed, U. F. S., & Arold, S. T. (2019). Passenger sequences can promote interlaced dimers in a common variant of the maltose-binding protein. Scientific Reports, 9(1).